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Squeezing through the microcirculation: survival adaptations of circulating tumour cells to seed metastasis
During metastasis, tumour cells navigating the vascular circulatory system—circulating tumour cells (CTCs)—encounter capillary beds, where they start the process of extravasation. Biomechanical constriction forces exerted by the microcirculation compromise the survival of tumour cells within capilla...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782506/ https://www.ncbi.nlm.nih.gov/pubmed/33257836 http://dx.doi.org/10.1038/s41416-020-01176-x |