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Squeezing through the microcirculation: survival adaptations of circulating tumour cells to seed metastasis

During metastasis, tumour cells navigating the vascular circulatory system—circulating tumour cells (CTCs)—encounter capillary beds, where they start the process of extravasation. Biomechanical constriction forces exerted by the microcirculation compromise the survival of tumour cells within capilla...

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Detalles Bibliográficos
Autores principales: Perea Paizal, Julia, Au, Sam H., Bakal, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782506/
https://www.ncbi.nlm.nih.gov/pubmed/33257836
http://dx.doi.org/10.1038/s41416-020-01176-x