ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function

CCCTC binding factor (CTCF) is an important factor in the maintenance of chromatin–chromatin interactions, yet the mechanism regulating its binding to chromatin is unknown. We demonstrate that zinc finger protein 143 (ZNF143) is a key regulator for CTCF-bound promoter–enhancer loops. In the murine g...

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Detalles Bibliográficos
Autores principales: Zhou, Qiling, Yu, Miao, Tirado-Magallanes, Roberto, Li, Bin, Kong, Lingshi, Guo, Mingrui, Tan, Zi Hui, Lee, Sanghoon, Chai, Li, Numata, Akihiko, Benoukraf, Touati, Fullwood, Melissa Jane, Osato, Motomi, Ren, Bing, Tenen, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782510/
https://www.ncbi.nlm.nih.gov/pubmed/33397967
http://dx.doi.org/10.1038/s41467-020-20282-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782510/
https://www.ncbi.nlm.nih.gov/pubmed/33397967
http://dx.doi.org/10.1038/s41467-020-20282-1

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