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The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence
Brain metastases are a major cause of melanoma-related mortality and morbidity. We undertook whole-exome sequencing of 50 tumours from patients undergoing surgical resection of brain metastases presenting as the first site of visceral disease spread and validated our findings in an independent datas...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782512/ https://www.ncbi.nlm.nih.gov/pubmed/33024263 http://dx.doi.org/10.1038/s41416-020-01090-2 |