The mutational landscape of melanoma brain metastases presenting as the first visceral site of recurrence

Brain metastases are a major cause of melanoma-related mortality and morbidity. We undertook whole-exome sequencing of 50 tumours from patients undergoing surgical resection of brain metastases presenting as the first site of visceral disease spread and validated our findings in an independent datas...

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Detalles Bibliográficos
Autores principales: Rabbie, Roy, Ferguson, Peter, Wong, Kim, Couturier, Dominique-Laurent, Moran, Una, Turner, Clinton, Emanuel, Patrick, Haas, Kerstin, Saunus, Jodi M., Davidson, Morgan R., Lakhani, Sunil R., Shivalingam, Brindha, Long, Georgina V., Parkinson, Christine, Osman, Iman, Scolyer, Richard A., Corrie, Pippa, Adams, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782512/
https://www.ncbi.nlm.nih.gov/pubmed/33024263
http://dx.doi.org/10.1038/s41416-020-01090-2

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