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p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

Autophagy contributes to the selective degradation of liquid droplets, including the P-Granule, Ape1-complex and p62/SQSTM1-body, although the molecular mechanisms and physiological relevance of selective degradation remain unclear. In this report, we describe the properties of endogenous p62-bodies...

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Detalles Bibliográficos
Autores principales: Kageyama, Shun, Gudmundsson, Sigurdur Runar, Sou, Yu-Shin, Ichimura, Yoshinobu, Tamura, Naoki, Kazuno, Saiko, Ueno, Takashi, Miura, Yoshiki, Noshiro, Daisuke, Abe, Manabu, Mizushima, Tsunehiro, Miura, Nobuaki, Okuda, Shujiro, Motohashi, Hozumi, Lee, Jin-A, Sakimura, Kenji, Ohe, Tomoyuki, Noda, Nobuo N., Waguri, Satoshi, Eskelinen, Eeva-Liisa, Komatsu, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782522/
https://www.ncbi.nlm.nih.gov/pubmed/33397898
http://dx.doi.org/10.1038/s41467-020-20185-1