Identification of PIM1 substrates reveals a role for NDRG1 phosphorylation in prostate cancer cellular migration and invasion

PIM1 is a serine/threonine kinase that promotes and maintains prostate tumorigenesis. While PIM1 protein levels are elevated in prostate cancer relative to local disease, the mechanisms by which PIM1 contributes to oncogenesis have not been fully elucidated. Here, we performed a direct, unbiased che...

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Detalles Bibliográficos
Autores principales: Ledet, Russell J., Ruff, Sophie E., Wang, Yu, Nayak, Shruti, Schneider, Jeffrey A., Ueberheide, Beatrix, Logan, Susan K., Garabedian, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782530/
https://www.ncbi.nlm.nih.gov/pubmed/33398037
http://dx.doi.org/10.1038/s42003-020-01528-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782530/
https://www.ncbi.nlm.nih.gov/pubmed/33398037
http://dx.doi.org/10.1038/s42003-020-01528-6

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