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Metastasis: crosstalk between tissue mechanics and tumour cell plasticity

Despite the fact that different genetic programmes drive metastasis of solid tumours, the ultimate outcome is the same: tumour cells are empowered to pass a series of physical hurdles to escape the primary tumour and disseminate to other organs. Epithelial-to-mesenchymal transition (EMT) has been pr...

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Detalles Bibliográficos
Autores principales: Coban, Bircan, Bergonzini, Cecilia, Zweemer, Annelien J. M., Danen, Erik H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782541/
https://www.ncbi.nlm.nih.gov/pubmed/33204023
http://dx.doi.org/10.1038/s41416-020-01150-7