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Nerve growth factor interacts with CHRM4 and promotes neuroendocrine differentiation of prostate cancer and castration resistance

Nerve growth factor (NGF) contributes to the progression of malignancy. However, the functional role and regulatory mechanisms of NGF in the development of neuroendocrine prostate cancer (NEPC) are unclear. Here, we show that an androgen-deprivation therapy (ADT)-stimulated transcription factor, ZBT...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Yu, Wen, Yu-Ching, Lin, Shian-Ren, Yeh, Hsiu-Lien, Jiang, Kuo-Ching, Chen, Wei-Hao, Lin, Yow-Sien, Zhang, Qingfu, Liew, Phui-Ly, Hsiao, Michael, Huang, Jiaoti, Liu, Yen-Nien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782543/
https://www.ncbi.nlm.nih.gov/pubmed/33398073
http://dx.doi.org/10.1038/s42003-020-01549-1