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Suppression of pancreatic cancer liver metastasis by secretion-deficient ITIH5

BACKGROUND: Previously, we identified ITIH5 as a suppressor of pancreatic ductal adenocarcinoma (PDAC) metastasis in experimental models. Expression of ITIH5 correlated with decreased cell motility, invasion and metastasis without significant inhibition of primary tumour growth. Here, we tested whet...

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Detalles Bibliográficos
Autores principales: Young, Eric D., Manley, Sharon J., Beadnell, Thomas C., Shearin, Alexander E., Sasaki, Ken, Zimmerman, Rosalyn, Kauffman, Evan, Vivian, Carolyn J., Parasuram, Aishwarya, Iwakuma, Tomoo, Grandgenett, Paul M., Hollingsworth, Michael A., O’Neil, Maura, Welch, Danny R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782545/
https://www.ncbi.nlm.nih.gov/pubmed/33024269
http://dx.doi.org/10.1038/s41416-020-01093-z