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Non-invasive assessment of telomere maintenance mechanisms in brain tumors

Telomere maintenance is a universal hallmark of cancer. Most tumors including low-grade oligodendrogliomas use telomerase reverse transcriptase (TERT) expression for telomere maintenance while astrocytomas use the alternative lengthening of telomeres (ALT) pathway. Although TERT and ALT are hallmark...

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Detalles Bibliográficos
Autores principales: Viswanath, Pavithra, Batsios, Georgios, Mukherjee, Joydeep, Gillespie, Anne Marie, Larson, Peder E. Z., Luchman, H. Artee, Phillips, Joanna J., Costello, Joseph F., Pieper, Russell O., Ronen, Sabrina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782549/
https://www.ncbi.nlm.nih.gov/pubmed/33397920
http://dx.doi.org/10.1038/s41467-020-20312-y