Cargando…
Non-invasive assessment of telomere maintenance mechanisms in brain tumors
Telomere maintenance is a universal hallmark of cancer. Most tumors including low-grade oligodendrogliomas use telomerase reverse transcriptase (TERT) expression for telomere maintenance while astrocytomas use the alternative lengthening of telomeres (ALT) pathway. Although TERT and ALT are hallmark...
Autores principales: | Viswanath, Pavithra, Batsios, Georgios, Mukherjee, Joydeep, Gillespie, Anne Marie, Larson, Peder E. Z., Luchman, H. Artee, Phillips, Joanna J., Costello, Joseph F., Pieper, Russell O., Ronen, Sabrina M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782549/ https://www.ncbi.nlm.nih.gov/pubmed/33397920 http://dx.doi.org/10.1038/s41467-020-20312-y |
Ejemplares similares
-
BIMG-02. IMAGING IMMORTALITY: TERT EXPRESSION ALTERS GLUCOSE METABOLISM IN LOW-GRADE GLIOMAS IN A MANNER THAT CAN BE LEVERAGED FOR NONINVASIVE METABOLIC IMAGING
por: Viswanath, Pavithra, et al.
Publicado: (2021) -
BIMG-05. TO BE OR NOT TO BE GLYCOLYTIC: DEUTERATED GLUCOSE-BASED ASSESSMENT OF THE WARBURG EFFECT ALLOWS NON-INVASIVE IMAGING OF TUMOR BURDEN AND TREATMENT RESPONSE IN MUTANT IDH GLIOMAS IN VIVO
por: Taglang, Celine, et al.
Publicado: (2021) -
TBMT-01. HYPERPOLARIZED δ-[1-(13)C]GLUCONOLACTONE MONITORS TERT-INDUCED ELEVATION IN PENTOSE PHOSPHATE PATHWAY FLUX IN BRAIN TUMORS IN VIVO
por: Batsios, Georgios, et al.
Publicado: (2021) -
Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma
por: Radoul, Marina, et al.
Publicado: (2021) -
BIMG-08. DEUTERIUM MAGNETIC RESONANCE SPECTROSCOPY USING (2)H-PYRUVATE ALLOWS NON-INVASIVE IN VIVO IMAGING OF TERT EXPRESSION IN BRAIN TUMORS
por: Batsios, Georgios, et al.
Publicado: (2021)