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The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

Age is a major risk factor for severe coronavirus disease-2019 (COVID-19). Here, we interrogate the transcriptional features and cellular landscape of the aging human lung. By intersecting these age-associated changes with experimental data on SARS-CoV-2, we identify several factors that may contrib...

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Detalles Bibliográficos
Autores principales: Chow, Ryan D., Majety, Medha, Chen, Sidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782551/
https://www.ncbi.nlm.nih.gov/pubmed/33397975
http://dx.doi.org/10.1038/s41467-020-20323-9