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Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction

Disorders of autophagy, a key regulator of cellular homeostasis, cause a number of human diseases. Due to the role of autophagy in metabolic dysregulation, there is a need to identify autophagy regulators as therapeutic targets. To address this need, we conducted an autophagy phenotype-based screen...

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Detalles Bibliográficos
Autores principales: Kim, Dasol, Hwang, Hui-Yun, Ji, Eun Sun, Kim, Jin Young, Yoo, Jong Shin, Kwon, Ho Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782552/
https://www.ncbi.nlm.nih.gov/pubmed/33398033
http://dx.doi.org/10.1038/s42003-020-01566-0