Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan

The intrinsic aerobic capacity of an organism is thought to play a role in aging and longevity. Maximal respiratory rate capacity, a metabolic performance measure, is one of the best predictors of cardiovascular- and all-cause mortality. Rats selectively bred for high-(HCR) vs. low-(LCR) intrinsic r...

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Detalles Bibliográficos
Autores principales: Aon, Miguel A., Cortassa, Sonia, Juhaszova, Magdalena, González-Reyes, José A., Calvo-Rubio, Miguel, Villalba, José M., Lachance, Andrew D., Ziman, Bruce D., Mitchell, Sarah J., Murt, Kelsey N., Axsom, Jessie E. C., Alfaras, Irene, Britton, Steven L., Koch, Lauren G., de Cabo, Rafael, Lakatta, Edward G., Sollott, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782588/
https://www.ncbi.nlm.nih.gov/pubmed/33398019
http://dx.doi.org/10.1038/s41514-020-00054-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782588/
https://www.ncbi.nlm.nih.gov/pubmed/33398019
http://dx.doi.org/10.1038/s41514-020-00054-3

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