Global computational alignment of tumor and cell line transcriptional profiles

Cell lines are key tools for preclinical cancer research, but it remains unclear how well they represent patient tumor samples. Direct comparisons of tumor and cell line transcriptional profiles are complicated by several factors, including the variable presence of normal cells in tumor samples. We...

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Detalles Bibliográficos
Autores principales: Warren, Allison, Chen, Yejia, Jones, Andrew, Shibue, Tsukasa, Hahn, William C., Boehm, Jesse S., Vazquez, Francisca, Tsherniak, Aviad, McFarland, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782593/
https://www.ncbi.nlm.nih.gov/pubmed/33397959
http://dx.doi.org/10.1038/s41467-020-20294-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782593/
https://www.ncbi.nlm.nih.gov/pubmed/33397959
http://dx.doi.org/10.1038/s41467-020-20294-x

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