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Spatiotemporal profiling of cytosolic signaling complexes in living cells by selective proximity proteomics
Signaling complexes are often organized in a spatiotemporal manner and on a minute timescale. Proximity labeling based on engineered ascorbate peroxidase APEX2 pioneered in situ capture of spatiotemporal membrane protein complexes in living cells, but its application to cytosolic proteins remains li...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782698/ https://www.ncbi.nlm.nih.gov/pubmed/33397984 http://dx.doi.org/10.1038/s41467-020-20367-x |