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Spatiotemporal profiling of cytosolic signaling complexes in living cells by selective proximity proteomics

Signaling complexes are often organized in a spatiotemporal manner and on a minute timescale. Proximity labeling based on engineered ascorbate peroxidase APEX2 pioneered in situ capture of spatiotemporal membrane protein complexes in living cells, but its application to cytosolic proteins remains li...

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Detalles Bibliográficos
Autores principales: Ke, Mi, Yuan, Xiao, He, An, Yu, Peiyuan, Chen, Wendong, Shi, Yu, Hunter, Tony, Zou, Peng, Tian, Ruijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782698/
https://www.ncbi.nlm.nih.gov/pubmed/33397984
http://dx.doi.org/10.1038/s41467-020-20367-x