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Spatiotemporal profiling of cytosolic signaling complexes in living cells by selective proximity proteomics
Signaling complexes are often organized in a spatiotemporal manner and on a minute timescale. Proximity labeling based on engineered ascorbate peroxidase APEX2 pioneered in situ capture of spatiotemporal membrane protein complexes in living cells, but its application to cytosolic proteins remains li...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782698/ https://www.ncbi.nlm.nih.gov/pubmed/33397984 http://dx.doi.org/10.1038/s41467-020-20367-x |