Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases

Aging and fertility are two interconnected processes. From invertebrates to mammals, absence of the germline increases longevity. Here we show that loss of function of sul-2, the Caenorhabditis elegans steroid sulfatase (STS), raises the pool of sulfated steroid hormones, increases longevity and ame...

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Detalles Bibliográficos
Autores principales: Pérez-Jiménez, Mercedes M., Monje-Moreno, José M., Brokate-Llanos, Ana María, Venegas-Calerón, Mónica, Sánchez-García, Alicia, Sansigre, Paula, Valladares, Amador, Esteban-García, Sara, Suárez-Pereira, Irene, Vitorica, Javier, Ríos, José Julián, Artal-Sanz, Marta, Carrión, Ángel M., Muñoz, Manuel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782729/
https://www.ncbi.nlm.nih.gov/pubmed/33397961
http://dx.doi.org/10.1038/s41467-020-20269-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782729/
https://www.ncbi.nlm.nih.gov/pubmed/33397961
http://dx.doi.org/10.1038/s41467-020-20269-y

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