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Cellular proteostasis decline in human senescence

A huge amount of intrigue surrounds the aging process. Senescence—the decreased likelihood of reproduction and the increased chance of mortality—is a hallmark of aging. The reduced ability of senescent cells to maintain protein homeostasis (proteostasis) has been well-established in nematodes but th...

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Detalles Bibliográficos
Autor principal: Montague-Cardoso, Karli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782732/
https://www.ncbi.nlm.nih.gov/pubmed/33398007
http://dx.doi.org/10.1038/s42003-020-01578-w