Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques

Lassa virus (LASV) is endemic in West Africa and induces a viral hemorrhagic fever (VHF) with up to 30% lethality among clinical cases. The mechanisms involved in control of Lassa fever or, in contrast, the ensuing catastrophic illness and death are poorly understood. We used the cynomolgus monkey m...

Descripción completa

Detalles Bibliográficos
Autores principales: Baillet, Nicolas, Reynard, Stéphanie, Perthame, Emeline, Hortion, Jimmy, Journeaux, Alexandra, Mateo, Mathieu, Carnec, Xavier, Schaeffer, Justine, Picard, Caroline, Barrot, Laura, Barron, Stéphane, Vallve, Audrey, Duthey, Aurélie, Jacquot, Frédéric, Boehringer, Cathy, Jouvion, Grégory, Pietrosemoli, Natalia, Legendre, Rachel, Dillies, Marie-Agnès, Allan, Richard, Legras-Lachuer, Catherine, Carbonnelle, Caroline, Raoul, Hervé, Baize, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782745/
https://www.ncbi.nlm.nih.gov/pubmed/33398113
http://dx.doi.org/10.1038/s42003-020-01543-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782745/
https://www.ncbi.nlm.nih.gov/pubmed/33398113
http://dx.doi.org/10.1038/s42003-020-01543-7

Ejemplares similares