Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques

Lassa virus (LASV) is endemic in West Africa and induces a viral hemorrhagic fever (VHF) with up to 30% lethality among clinical cases. The mechanisms involved in control of Lassa fever or, in contrast, the ensuing catastrophic illness and death are poorly understood. We used the cynomolgus monkey m...

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Detalles Bibliográficos
Autores principales: Baillet, Nicolas, Reynard, Stéphanie, Perthame, Emeline, Hortion, Jimmy, Journeaux, Alexandra, Mateo, Mathieu, Carnec, Xavier, Schaeffer, Justine, Picard, Caroline, Barrot, Laura, Barron, Stéphane, Vallve, Audrey, Duthey, Aurélie, Jacquot, Frédéric, Boehringer, Cathy, Jouvion, Grégory, Pietrosemoli, Natalia, Legendre, Rachel, Dillies, Marie-Agnès, Allan, Richard, Legras-Lachuer, Catherine, Carbonnelle, Caroline, Raoul, Hervé, Baize, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782745/
https://www.ncbi.nlm.nih.gov/pubmed/33398113
http://dx.doi.org/10.1038/s42003-020-01543-7

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