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Epicutaneous immunization with modified vaccinia Ankara viral vectors generates superior T cell immunity against a respiratory viral challenge

Modified Vaccinia Ankara (MVA) was recently approved as a smallpox vaccine. Variola is transmitted by respiratory droplets and MVA immunization by skin scarification (s.s.) protected mice far more effectively against lethal respiratory challenge with vaccinia virus (VACV) than any other route of del...

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Detalles Bibliográficos
Autores principales: Pan, Youdong, Liu, Luzheng, Tian, Tian, Zhao, Jingxia, Park, Chang Ook, Lofftus, Serena Y., Stingley, Claire A., Yan, Yu, Mei, Shenglin, Liu, Xing, Kupper, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782760/
https://www.ncbi.nlm.nih.gov/pubmed/33398010
http://dx.doi.org/10.1038/s41541-020-00265-5