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Epicutaneous immunization with modified vaccinia Ankara viral vectors generates superior T cell immunity against a respiratory viral challenge
Modified Vaccinia Ankara (MVA) was recently approved as a smallpox vaccine. Variola is transmitted by respiratory droplets and MVA immunization by skin scarification (s.s.) protected mice far more effectively against lethal respiratory challenge with vaccinia virus (VACV) than any other route of del...
Autores principales: | Pan, Youdong, Liu, Luzheng, Tian, Tian, Zhao, Jingxia, Park, Chang Ook, Lofftus, Serena Y., Stingley, Claire A., Yan, Yu, Mei, Shenglin, Liu, Xing, Kupper, Thomas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782760/ https://www.ncbi.nlm.nih.gov/pubmed/33398010 http://dx.doi.org/10.1038/s41541-020-00265-5 |
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