A single day of TGF-β1 exposure activates chondrogenic and hypertrophic differentiation pathways in bone marrow-derived stromal cells

Virtually all bone marrow-derived stromal cell (BMSC) chondrogenic induction cultures include greater than 2 weeks exposure to transforming growth factor-β (TGF-β), but fail to generate cartilage-like tissue suitable for joint repair. Herein we used a micro-pellet model (5 × 10(3) BMSC each) to dete...

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Detalles Bibliográficos
Autores principales: Futrega, Kathryn, Robey, Pamela G., Klein, Travis J., Crawford, Ross W., Doran, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782775/
https://www.ncbi.nlm.nih.gov/pubmed/33398032
http://dx.doi.org/10.1038/s42003-020-01520-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782775/
https://www.ncbi.nlm.nih.gov/pubmed/33398032
http://dx.doi.org/10.1038/s42003-020-01520-0

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