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A single day of TGF-β1 exposure activates chondrogenic and hypertrophic differentiation pathways in bone marrow-derived stromal cells

Virtually all bone marrow-derived stromal cell (BMSC) chondrogenic induction cultures include greater than 2 weeks exposure to transforming growth factor-β (TGF-β), but fail to generate cartilage-like tissue suitable for joint repair. Herein we used a micro-pellet model (5 × 10(3) BMSC each) to dete...

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Detalles Bibliográficos
Autores principales:	Futrega, Kathryn, Robey, Pamela G., Klein, Travis J., Crawford, Ross W., Doran, Michael R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782775/ https://www.ncbi.nlm.nih.gov/pubmed/33398032 http://dx.doi.org/10.1038/s42003-020-01520-0

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