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Probing the influence of mutations on FUS condensates, one molecule at a time

Protein aggregation and phase separation appear to play important roles in diseases like amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD), but the interplay between different participating molecular events-which may facilitate or inhibit one another-can be difficult to st...

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Detalles Bibliográficos
Autor principal: Chattopadhyay, Krishnananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782781/
https://www.ncbi.nlm.nih.gov/pubmed/33398047
http://dx.doi.org/10.1038/s42003-020-01560-6