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Probing the influence of mutations on FUS condensates, one molecule at a time
Protein aggregation and phase separation appear to play important roles in diseases like amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD), but the interplay between different participating molecular events-which may facilitate or inhibit one another-can be difficult to st...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782781/ https://www.ncbi.nlm.nih.gov/pubmed/33398047 http://dx.doi.org/10.1038/s42003-020-01560-6 |