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TRAIL receptor-induced features of epithelial-to-mesenchymal transition increase tumour phenotypic heterogeneity: potential cell survival mechanisms

The continuing efforts to exploit the death receptor agonists, such as the tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), for cancer therapy, have largely been impaired by the anti-apoptotic and pro-survival signalling pathways leading to drug resistance. Cell migration, inv...

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Detalles Bibliográficos
Autores principales: Peyre, Ludovic, Meyer, Mickael, Hofman, Paul, Roux, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782794/
https://www.ncbi.nlm.nih.gov/pubmed/33257838
http://dx.doi.org/10.1038/s41416-020-01177-w