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Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages
Pro-inflammatory activation of adipose tissue macrophages (ATMs) is causally linked to obesity and obesity-associated disorders. A number of studies have demonstrated the crucial role of mitochondrial metabolism in macrophage activation. However, there is a lack of pharmaceutical agents to target th...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782823/ https://www.ncbi.nlm.nih.gov/pubmed/33397994 http://dx.doi.org/10.1038/s41467-020-20315-9 |