Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages

Pro-inflammatory activation of adipose tissue macrophages (ATMs) is causally linked to obesity and obesity-associated disorders. A number of studies have demonstrated the crucial role of mitochondrial metabolism in macrophage activation. However, there is a lack of pharmaceutical agents to target th...

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Detalles Bibliográficos
Autores principales: Wang, Yawei, Tang, Binlin, Long, Lei, Luo, Peng, Xiang, Wei, Li, Xueru, Wang, Huilan, Jiang, Qingzhi, Tan, Xu, Luo, Shenglin, Li, Huijuan, Wang, Ziwen, Chen, Zelin, Leng, Yu, Jiang, Zhongyong, Wang, Yang, Ma, Le, Wang, Rui, Zeng, Chunyu, Liu, Zujuan, Wang, Yu, Miao, Hongming, Shi, Chunmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782823/
https://www.ncbi.nlm.nih.gov/pubmed/33397994
http://dx.doi.org/10.1038/s41467-020-20315-9

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