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Insights into the role of sialylation in cancer progression and metastasis

Upregulation of sialyltransferases—the enzymes responsible for the addition of sialic acid to growing glycoconjugate chains—and the resultant hypersialylation of up to 40–60% of tumour cell surfaces are established hallmarks of several cancers, including lung, breast, ovarian, pancreatic and prostat...

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Detalles Bibliográficos
Autores principales: Dobie, Christopher, Skropeta, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782833/
https://www.ncbi.nlm.nih.gov/pubmed/33144696
http://dx.doi.org/10.1038/s41416-020-01126-7