Nme1 and Nme2 genes exert metastasis-suppressor activities in a genetically engineered mouse model of UV-induced melanoma

NME1 is a metastasis-suppressor gene (MSG), capable of suppressing metastatic activity in cell lines of melanoma, breast carcinoma and other cancer origins without affecting their growth in culture or as primary tumours. Herein, we selectively ablated the tandemly arranged Nme1 and Nme2 genes to ass...

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Detalles Bibliográficos
Autores principales: Pamidimukkala, Nidhi, Puts, Gemma S., Kathryn Leonard, M., Snyder, Devin, Dabernat, Sandrine, De Fabo, Edward C., Noonan, Frances P., Slominski, Andrzej, Merlino, Glenn, Kaetzel, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782836/
https://www.ncbi.nlm.nih.gov/pubmed/33024267
http://dx.doi.org/10.1038/s41416-020-01096-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782836/
https://www.ncbi.nlm.nih.gov/pubmed/33024267
http://dx.doi.org/10.1038/s41416-020-01096-w

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