Homeostatic regulation of STING by retrograde membrane traffic to the ER

Coat protein complex I (COP-I) mediates the retrograde transport from the Golgi apparatus to the endoplasmic reticulum (ER). Mutation of the COPA gene, encoding one of the COP-I subunits (α-COP), causes an immune dysregulatory disease known as COPA syndrome. The molecular mechanism by which the impa...

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Detalles Bibliográficos
Autores principales: Mukai, Kojiro, Ogawa, Emari, Uematsu, Rei, Kuchitsu, Yoshihiko, Kiku, Fumika, Uemura, Takefumi, Waguri, Satoshi, Suzuki, Takehiro, Dohmae, Naoshi, Arai, Hiroyuki, Shum, Anthony K., Taguchi, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782846/
https://www.ncbi.nlm.nih.gov/pubmed/33397928
http://dx.doi.org/10.1038/s41467-020-20234-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782846/
https://www.ncbi.nlm.nih.gov/pubmed/33397928
http://dx.doi.org/10.1038/s41467-020-20234-9

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