CDX2 inhibits epithelial–mesenchymal transition in colorectal cancer by modulation of Snail expression and β-catenin stabilisation via transactivation of PTEN expression

BACKGROUND: Emerging evidence suggests the involvement of caudal-related homoeobox transcription factor 2 (CDX2) in tumorigenesis of various cancers. Although CDX2 functions in cancer invasion and metastasis, fewer studies focus on the role of CDX2 during the induction of epithelial–mesenchymal tran...

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Detalles Bibliográficos
Autores principales: Yu, Junhui, Li, Shan, Xu, Zhengshui, Guo, Jing, Li, Xiaopeng, Wu, Yunhua, Zheng, Jianbao, Sun, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782852/
https://www.ncbi.nlm.nih.gov/pubmed/33239678
http://dx.doi.org/10.1038/s41416-020-01148-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782852/
https://www.ncbi.nlm.nih.gov/pubmed/33239678
http://dx.doi.org/10.1038/s41416-020-01148-1

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