Cargando…
CDX2 inhibits epithelial–mesenchymal transition in colorectal cancer by modulation of Snail expression and β-catenin stabilisation via transactivation of PTEN expression
BACKGROUND: Emerging evidence suggests the involvement of caudal-related homoeobox transcription factor 2 (CDX2) in tumorigenesis of various cancers. Although CDX2 functions in cancer invasion and metastasis, fewer studies focus on the role of CDX2 during the induction of epithelial–mesenchymal tran...
Autores principales: | Yu, Junhui, Li, Shan, Xu, Zhengshui, Guo, Jing, Li, Xiaopeng, Wu, Yunhua, Zheng, Jianbao, Sun, Xuejun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782852/ https://www.ncbi.nlm.nih.gov/pubmed/33239678 http://dx.doi.org/10.1038/s41416-020-01148-1 |
Ejemplares similares
-
CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression
por: Yu, Junhui, et al.
Publicado: (2019) -
Farnesoid X receptor activation induces antitumour activity in colorectal cancer by suppressing JAK2/STAT3 signalling via transactivation of SOCS3 gene
por: Li, Shan, et al.
Publicado: (2020) -
Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo
por: Zheng, Jianbao, et al.
Publicado: (2017) -
Farnesoid X receptor antagonizes Wnt/β-catenin signaling in colorectal tumorigenesis
por: Yu, Junhui, et al.
Publicado: (2020) -
Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin
por: Xu, Zhengshui, et al.
Publicado: (2021)