Evaluation of neurobiological and antioxidant effects of novel melatonin analogs in mice

Based on the pharmacophore model of melatonin (MT(1)) receptor, we recently synthesized a series of indole derivatives that showed anticonvulsant activity with low neurotoxicity and hepatotoxicity in rodents. In the present study, the three most potent C3-modified derivatives with hydrazine structur...

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Detalles Bibliográficos
Autores principales: Tchekalarova, Jana, Ivanova, Natasha, Nenchovska, Zlatina, Tzoneva, Rumiana, Stoyanova, Tzveta, Uzunova, Veselina, Surcheva, Slavina, Tzonev, Alex, T. Angelova, Violina, Andreeva-Gateva, Pavlina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783092/
https://www.ncbi.nlm.nih.gov/pubmed/33424250
http://dx.doi.org/10.1016/j.jsps.2020.10.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783092/
https://www.ncbi.nlm.nih.gov/pubmed/33424250
http://dx.doi.org/10.1016/j.jsps.2020.10.004

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