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Fraxetin inhibits interleukin-1β-induced apoptosis, inflammation, and matrix degradation in chondrocytes and protects rat cartilage in vivo

Osteoarthritis (OA) is a disease characterized by degeneration of the joint complex due to cartilage destruction. Fraxetin, a widely used and studied coumarin compound extracted from a traditional Chinese herb (Qin Pi), has shown anti-inflammatory and antioxidant properties, but its effects on OA ha...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Zhuang, Di, Feng, Wenchang, Ma, Bitao, Qin, Liping, Jin, Lilun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783108/
https://www.ncbi.nlm.nih.gov/pubmed/33424243
http://dx.doi.org/10.1016/j.jsps.2020.09.016