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Unsupervised Inference of Protein Fitness Landscape from Deep Mutational Scan
The recent technological advances underlying the screening of large combinatorial libraries in high-throughput mutational scans deepen our understanding of adaptive protein evolution and boost its applications in protein design. Nevertheless, the large number of possible genotypes requires suitable...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783173/ https://www.ncbi.nlm.nih.gov/pubmed/32770229 http://dx.doi.org/10.1093/molbev/msaa204 |