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Hydrogel-based matrices for controlled drug delivery of etamsylate: Prediction of in-vivo plasma profiles

OBJECTIVES: To design oral controlled release (CR) hydrogel matrix tablets of etamsylate using various hydrophilic polymers. Additionally, to predict plasma concentration-time profiles of etamsylate released from different CR matrices. METHODS: Characterization of the in-vitro release rate was perfo...

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Detalles Bibliográficos
Autores principales: El-Masry, Soha M., Helmy, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783234/
https://www.ncbi.nlm.nih.gov/pubmed/33424262
http://dx.doi.org/10.1016/j.jsps.2020.10.016