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Interaction between Peptidyl-prolyl Cis-trans Isomerase NIMA-interacting 1 and GTP-H-Ras: Implications for Aggressiveness of Human Mammary Epithelial Cells and Drug Resistance

Aberrant activation of Ras has been implicated in aggressiveness of breast cancer. Among Ras isoforms (H-, K-, and N-), H-Ras has been known to be primarily responsible for invasion and metastasis of breast cancer cells. Phosphorylation of serine (Ser) or threonine (Thr) is a key regulatory mechanis...

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Detalles Bibliográficos
Autores principales: Saeidi, Soma, Joo, Sihyung, Kim, Su-Jung, Jagadeesh, Achanta Sri Venkata, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783236/
https://www.ncbi.nlm.nih.gov/pubmed/33409256
http://dx.doi.org/10.15430/JCP.2020.25.4.234