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Unique Properties of the Alpha-Helical DNA-Binding Protein KfrA Encoded by the IncU Incompatibility Group Plasmid RA3 and Its Host-Dependent Role in Plasmid Maintenance

KfrA, encoded on the broad-host-range RA3 plasmid, is an alpha-helical DNA-binding protein that acts as a transcriptional autoregulator. The KfrA(RA3) operator site overlaps the kfrA promoter and is composed of five 9-bp direct repeats (DRs). Here, the biological properties of KfrA were studied usin...

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Detalles Bibliográficos
Autores principales: Lewicka, Ewa, Mitura, Monika, Steczkiewicz, Kamil, Kieracinska, Justyna, Skrzynska, Kamila, Adamczyk, Malgorzata, Jagura-Burdzy, Grazyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783346/
https://www.ncbi.nlm.nih.gov/pubmed/33097508
http://dx.doi.org/10.1128/AEM.01771-20