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Heme as Possible Contributing Factor in the Evolvement of Shiga-Toxin Escherichia coli Induced Hemolytic-Uremic Syndrome

Shiga-toxin (Stx)-producing Escherichia coli hemolytic-uremic syndrome (STEC-HUS) is one of the most common causes of acute kidney injury in children. Stx-mediated endothelial injury initiates the cascade leading to thrombotic microangiopathy (TMA), still the exact pathogenesis remains elusive. Inte...

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Detalles Bibliográficos
Autores principales: Wijnsma, Kioa L., Veissi, Susan T., de Wijs, Sem, van der Velden, Thea, Volokhina, Elena B., Wagener, Frank A. D. T. G., van de Kar, Nicole. C. A. J., van den Heuvel, L. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783363/
https://www.ncbi.nlm.nih.gov/pubmed/33414780
http://dx.doi.org/10.3389/fimmu.2020.547406