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Experimental Nanovaccine Offers Protection Against Repeat Exposures to Trypanosoma cruzi Through Activation of Polyfunctional T Cell Response

A parasitic protozoan Trypanosoma cruzi (T. cruzi) is the etiologic agent of Chagas disease. Previously, we have identified T. cruzi antigens TcG2 and TcG4 as potential vaccine candidates, cloned in eukaryotic expression vector pCDNA3.1 (referred as p2/4) and tested their ability to elicit protectio...

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Detalles Bibliográficos
Autores principales: Chowdhury, Imran H., Lokugamage, Nandadeva, Garg, Nisha Jain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783422/
https://www.ncbi.nlm.nih.gov/pubmed/33414785
http://dx.doi.org/10.3389/fimmu.2020.595039