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Biophysical Characterization of a Novel SCN5A Mutation Associated With an Atypical Phenotype of Atrial and Ventricular Arrhythmias and Sudden Death

BACKGROUND: Sudden cardiac death (SCD) is an unexpected death that occurs within an hour of the onset of symptoms. Hereditary primary electrical disorders account for up to 1/3 of all SCD cases in younger individuals and include conditions such as catecholaminergic polymorphic ventricular tachycardi...

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Detalles Bibliográficos
Autores principales: Ghovanloo, Mohammad-Reza, Atallah, Joseph, Escudero, Carolina A., Ruben, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783455/
https://www.ncbi.nlm.nih.gov/pubmed/33414724
http://dx.doi.org/10.3389/fphys.2020.610436