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Prevention of hepatic encephalopathy by administration of rifaximin and lactulose in patients with liver cirrhosis undergoing placement of a transjugular intrahepatic portosystemic shunt (TIPS): a multicentre randomised, double blind, placebo controlled trial (PEARL trial)

INTRODUCTION: Cirrhotic patients with portal hypertension can suffer from variceal bleeding or refractory ascites and can benefit from a transjugular intrahepatic portosystemic shunt (TIPS). Post-TIPS hepatic encephalopathy (HE) is a common (20%–54%) and often severe complication. A prophylactic str...

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Detalles Bibliográficos
Autores principales: de Wit, K, Schaapman, J J, Nevens, F, Verbeek, J, Coenen, S, Cuperus, F J C, Kramer, M, Tjwa, E T T L, Mostafavi, N, Dijkgraaf, M G W, van Delden, O M, Beuers, U H W, Coenraad, M J, Takkenberg, R B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783616/
https://www.ncbi.nlm.nih.gov/pubmed/33372103
http://dx.doi.org/10.1136/bmjgast-2020-000531