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Regioselectivity of Cobalamin‐Dependent Methyltransferase Can Be Tuned by Reaction Conditions and Substrate

Regioselective reactions represent a significant challenge for organic chemistry. Here the regioselective methylation of a single hydroxy group of 4‐substituted catechols was investigated employing the cobalamin‐dependent methyltransferase from Desulfitobacterium hafniense. Catechols substituted in...

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Detalles Bibliográficos
Autores principales: Pompei, Simona, Grimm, Christopher, Farnberger, Judith E., Schober, Lukas, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783988/
https://www.ncbi.nlm.nih.gov/pubmed/33442427
http://dx.doi.org/10.1002/cctc.202001296