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Conditional genetic deletion of CSF1 receptor in microglia ameliorates the physiopathology of Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common form of dementia in the world. Microglia are the innate immune cells of CNS; their proliferation, activation, and survival in pathologic and healthy brain have previously been shown to be highly depe...

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Detalles Bibliográficos
Autores principales: Pons, Vincent, Lévesque, Pascal, Plante, Marie-Michèle, Rivest, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783991/
https://www.ncbi.nlm.nih.gov/pubmed/33402196
http://dx.doi.org/10.1186/s13195-020-00747-7