The degree of microsatellite instability predicts response to PD-1 blockade immunotherapy in mismatch repair-deficient/microsatellite instability-high colorectal cancers

The development of programmed cell death-1 inhibitor (PD-1) has shed light on the treatment of tumors with deficiencies in DNA mismatch repair system or microsatellite instability (dMMR/MSI). However, predicting the subset in this group that will benefit from PD-1 blockade remains a challenge. In th...

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Detalles Bibliográficos
Autores principales: Wang, Qiao-Xuan, Qu, Chun-Hua, Gao, Yuan-Hong, Ding, Pei-Rong, Yun, Jing-Ping, Xie, Dan, Cai, Mu-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784284/
https://www.ncbi.nlm.nih.gov/pubmed/33397433
http://dx.doi.org/10.1186/s40164-020-00193-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784284/
https://www.ncbi.nlm.nih.gov/pubmed/33397433
http://dx.doi.org/10.1186/s40164-020-00193-z

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