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Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice

BACKGROUND: Hyposmia in Alzheimer’s disease (AD) is a typical early symptom according to numerous previous clinical studies. Although amyloid-β (Aβ), which is one of the toxic factors upregulated early in AD, has been identified in many studies, even in the peripheral areas of the olfactory system,...

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Detalles Bibliográficos
Autores principales: Son, Gowoon, Yoo, Seung-Jun, Kang, Shinwoo, Rasheed, Ameer, Jung, Da Hae, Park, Hyunjun, Cho, Bongki, Steinbusch, Harry W. M., Chang, Keun-A, Suh, Yoo-Hun, Moon, Cheil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784287/
https://www.ncbi.nlm.nih.gov/pubmed/33397474
http://dx.doi.org/10.1186/s13195-020-00730-2