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The role of activating transcription factor 6 in hydroxycamptothecin-induced fibroblast autophagy and apoptosis

BACKGROUND: The over-proliferation of fibroblasts is considered to be the main cause of scar adhesion after joint surgery. Hydroxycamptothecin (HCPT), though as a potent antineoplastic drug, shows preventive effects on scar adhesion. This study aimed to investigate the role of activating transcripti...

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Detalles Bibliográficos
Autores principales: Tao, Jin, Chen, Hui, Li, Xiaolei, Wang, Jingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784342/
https://www.ncbi.nlm.nih.gov/pubmed/33397415
http://dx.doi.org/10.1186/s13018-020-02056-z