Cargando…

The role of activating transcription factor 6 in hydroxycamptothecin-induced fibroblast autophagy and apoptosis

BACKGROUND: The over-proliferation of fibroblasts is considered to be the main cause of scar adhesion after joint surgery. Hydroxycamptothecin (HCPT), though as a potent antineoplastic drug, shows preventive effects on scar adhesion. This study aimed to investigate the role of activating transcripti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tao, Jin, Chen, Hui, Li, Xiaolei, Wang, Jingcheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784342/ https://www.ncbi.nlm.nih.gov/pubmed/33397415 http://dx.doi.org/10.1186/s13018-020-02056-z

Ejemplares similares

Upregulation of NOXA by 10-Hydroxycamptothecin plays a key role in inducing fibroblasts apoptosis and reducing epidural fibrosis
por: Dai, Jihang, et al.
Publicado: (2017)

10-Hydroxycamptothecin induces apoptosis in human fibroblasts by regulating miRNA-23b-3p expression
por: Zeng, Lingrong, et al.
Publicado: (2019)

Hydroxycamptothecin mediates antiproliferative effects through apoptosis and autophagy in A549 cells
por: Wei, Yanjie, et al.
Publicado: (2018)

The optimal concentration of topical hydroxycamptothecin in preventing intraarticular scar adhesion
por: Liang, Yuan, et al.
Publicado: (2014)

Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression
por: Fei, Bojian, et al.
Publicado: (2013)

Hydroxycamptothecin Inhibits Peritendinous Adhesion via the Endoplasmic Reticulum Stress-Dependent Apoptosis
por: Yao, Zhixiao, et al.
Publicado: (2019)

The Role of Glucuronidation in 7‐Ethyl‐10‐hydroxycamptothecin Resistance in vitro
por: Takahashi, Toshiaki, et al.
Publicado: (1997)

Hydroxycamptothecin regulates scar formation of the filtration channel under scleral flap by inhibiting the proliferation of scleral fibroblasts
por: Gu, Hongwei, et al.
Publicado: (2023)

Role of Raf-kinase inhibitor protein in colorectal cancer and its regulation by hydroxycamptothecine
por: Nie, Fang, et al.
Publicado: (2015)

Synthetic high-density lipoproteins for delivery of 10-hydroxycamptothecin
por: Yuan, Yue, et al.
Publicado: (2016)

Effect of verapamil on the pharmacokinetics of hydroxycamptothecin and its potential mechanism
por: Xing, Hua, et al.
Publicado: (2020)

Emodin promotes fibroblast apoptosis and prevents epidural fibrosis through PERK pathway in rats
por: Xiong, Guirun, et al.
Publicado: (2019)

The effect of hydroxycamptothecin and pingyangmycin on human squamous cell carcinoma of the tongue
por: CHEN, PENG, et al.
Publicado: (2013)

Advances in Antitumor Nano-Drug Delivery Systems of 10-Hydroxycamptothecin
por: Chen, Yukun, et al.
Publicado: (2022)

Effects of nanoparticle size on antitumor activity of 10-hydroxycamptothecin-conjugated gold nanoparticles: in vitro and in vivo studies
por: Bao, Hanmei, et al.
Publicado: (2016)

Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect
por: Wang, Anxun, et al.
Publicado: (2008)

Preparation and in vitro and in vivo evaluations of 10-hydroxycamptothecin liposomes modified with stearyl glycyrrhetinate
por: Zhou, Ting, et al.
Publicado: (2019)

Menthol-modified casein nanoparticles loading 10-hydroxycamptothecin for glioma targeting therapy
por: Gao, Caifang, et al.
Publicado: (2019)

Preparation, Characterization, and in vivo Evaluation of NK4-Conjugated Hydroxycamptothecin-Loaded Liposomes
por: Zhou, Ting, et al.
Publicado: (2020)

Local application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis
por: Sun, Yu, et al.
Publicado: (2016)

Pseudolaric acid B induced autophagy, but not apoptosis, in MRC5 human fibroblast cells
por: Wang, Yue, et al.
Publicado: (2018)

Preparation and Physicochemical Properties of 10-Hydroxycamptothecin (HCPT) Nanoparticles by Supercritical Antisolvent (SAS) Process
por: Zhao, Xiuhua, et al.
Publicado: (2011)

Preparation of Carboxymethylchitosan Nanoparticles with Acid-Sensitive Bond Based on Solid Dispersion of 10-Hydroxycamptothecin
por: Yao, Risheng, et al.
Publicado: (2011)

Increased expression of DNA repair gene XPF enhances resistance to hydroxycamptothecin in bladder cancer
por: Li, Jie, et al.
Publicado: (2012)

Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects
por: Liu, Shuangxi, et al.
Publicado: (2019)

Development of 10-Hydroxycamptothecin-crizotinib conjugate based on the synergistic effect on lung cancer cells
por: Liu, Zhen, et al.
Publicado: (2022)

Fibroblast growth factor 23 regulates hypoxia‑induced osteoblast apoptosis through the autophagy‑signaling pathway
por: Yin, Qipu, et al.
Publicado: (2023)

Emodin induces apoptosis and autophagy of fibroblasts obtained from patient with ankylosing spondylitis
por: Ma, Cong, et al.
Publicado: (2019)

Human Serum Albumin Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN38) for Cancer Treatment
por: Sepehri, Nima, et al.
Publicado: (2014)

A Comparative Evaluation of Hydroxycamptothecin Drug Nanorods With and Without Methotrexate Prodrug Functionalization for Drug Delivery
por: Guo, Fuqiang, et al.
Publicado: (2016)

Synthesis and Biological Evaluation of Novel Water-Soluble Poly-(ethylene glycol)-10-hydroxycamptothecin Conjugates
por: Guo, Na, et al.
Publicado: (2015)

Antitumor Mechanism of Hydroxycamptothecin via the Metabolic Perturbation of Ribonucleotide and Deoxyribonucleotide in Human Colorectal Carcinoma Cells
por: Li, Yan, et al.
Publicado: (2021)

Neddylation inhibitor MLN4924 sensitizes head and neck squamous carcinoma cells to (S)-10-hydroxycamptothecin
por: Gu, Shanshan, et al.
Publicado: (2023)

LINC01605 knockdown induces apoptosis in human Tenon's capsule fibroblasts by inhibiting autophagy
por: Shang, Qifei, et al.
Publicado: (2022)

BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death
por: Relic, Biserka, et al.
Publicado: (2016)

Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway
por: Deng, Xiaohong, et al.
Publicado: (2020)

Exercise-induced FNDC5/irisin protects nucleus pulposus cells against senescence and apoptosis by activating autophagy
por: Zhou, Wenxian, et al.
Publicado: (2022)

Hyaluronic Acid Modified Hollow Prussian Blue Nanoparticles Loading 10-hydroxycamptothecin for Targeting Thermochemotherapy of Cancer
por: Jing, Lijia, et al.
Publicado: (2016)

Synthesis and Biological Evaluation of Novel 10-Substituted-7-ethyl-10-hydroxycamptothecin (SN-38) Prodrugs
por: Zhou, Mo, et al.
Publicado: (2014)

Oxidation modification of chitosan-based mesoporous carbon by soft template method and the adsorption and release properties of hydroxycamptothecin
por: Wang, Xianshu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_epsg77nd62totc4ecnridptcl1